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Gopala K Rangan Selected Research

3- amino- 6- (4- (methylsulfonyl)phenyl)- N- phenylpyrazine- 2- carboxamide

1/2021Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease.

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Gopala K Rangan Research Topics

Disease

16Cysts
09/2021 - 01/2007
15Proteinuria
01/2019 - 08/2001
12Autosomal Dominant Polycystic Kidney (ADPKD)
11/2021 - 05/2013
7Polycystic Kidney Diseases (Polycystic Kidney Disease)
10/2021 - 08/2009
6Inflammation (Inflammations)
01/2016 - 08/2001
5Chronic Renal Insufficiency
01/2020 - 02/2005
4Hypertension (High Blood Pressure)
01/2016 - 01/2007
4Necrosis
01/2014 - 01/2005
3Cystic Kidney Diseases (Cystic Kidney Disease)
01/2021 - 01/2006
3Disease Progression
11/2020 - 08/2009
3Complement Component 6 Deficiency
05/2016 - 11/2004
3Fibrosis (Cirrhosis)
12/2014 - 01/2006
3Atrophy
01/2006 - 08/2001
2Ataxia Telangiectasia (Louis Bar Syndrome)
01/2021 - 01/2021
2Body Weight (Weight, Body)
12/2014 - 08/2007
2Weight Gain
08/2013 - 03/2002
2Vitamin D Deficiency
08/2013 - 05/2013
2Glomerulonephritis
08/2009 - 01/2006
2Acute Kidney Injury (Acute Renal Failure)
08/2009 - 12/2005
2Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal)
08/2007 - 11/2004
2Nephrosis
10/2005 - 02/2005
1Mitochondrial Diseases (Mitochondrial Disease)
11/2021
1Weight Loss (Weight Reduction)
10/2021
1Gout
01/2020
1Heart Diseases (Heart Disease)
01/2016
1Pain (Aches)
05/2015
1Chronic Kidney Failure (Chronic Renal Failure)
02/2014
1Nephritis
01/2014
1Renal Insufficiency (Renal Failure)
05/2013
1Autosomal Recessive Polycystic Kidney (Polycystic Kidney Disease, Infantile, Type I)
01/2011
1Hyperuricemia
01/2011

Drug/Important Bio-Agent (IBA)

10Sirolimus (Rapamycin)FDA Link
09/2021 - 12/2005
7CreatinineIBA
01/2020 - 08/2001
6Proteins (Proteins, Gene)FDA Link
09/2021 - 12/2005
5Doxorubicin (Adriamycin)FDA LinkGeneric
08/2007 - 08/2001
3CalciumIBA
10/2021 - 05/2013
3DNA (Deoxyribonucleic Acid)IBA
09/2021 - 02/2006
3Uric Acid (Urate)IBA
01/2020 - 01/2011
3Complement Membrane Attack Complex (Membrane Attack Complex)IBA
05/2016 - 11/2004
2Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
10/2021 - 01/2006
2Calcitriol Receptors (Calcitriol Receptor)IBA
10/2021 - 05/2013
2Phosphotransferases (Kinase)IBA
09/2021 - 01/2021
2Messenger RNA (mRNA)IBA
09/2021 - 07/2016
2Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2021 - 08/2001
2Arginine (L-Arginine)FDA Link
01/2021 - 08/2001
2Nitric Oxide Synthase (NO Synthase)IBA
01/2021 - 08/2001
2SodiumIBA
11/2020 - 02/2005
2Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2020 - 01/2011
2Allopurinol (Remid)FDA LinkGeneric
01/2020 - 02/2014
2Biomarkers (Surrogate Marker)IBA
11/2019 - 05/2013
2Mechanistic Target of Rapamycin Complex 1IBA
01/2016 - 08/2009
2prolinedithiocarbamate (PDTC)IBA
12/2015 - 12/2014
2pyrrolidine dithiocarbamic acidIBA
12/2015 - 12/2014
2Vitamin DFDA LinkGeneric
08/2013 - 05/2013
2Cholecalciferol (Vitamin D3)FDA Link
08/2013 - 05/2013
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
05/2013 - 05/2013
2NF-kappa B (NF-kB)IBA
01/2005 - 08/2001
2Malondialdehyde (Propanedial)IBA
03/2002 - 08/2001
1TRPP Cation ChannelsIBA
11/2021
1paricalcitol (Zemplar)FDA Link
10/2021
1EnalaprilFDA LinkGeneric
10/2021
1Serine (L-Serine)FDA Link
09/2021
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
09/2021
18- dibenzothiophen- 4- yl- 2- morpholin- 4- yl- chromen- 4- oneIBA
09/2021
1Threonine (L-Threonine)FDA Link
09/2021
1A-Form DNA (A-DNA)IBA
09/2021
1DNA-Activated Protein KinaseIBA
09/2021
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
01/2021
1Protein Kinases (Protein Kinase)IBA
01/2021
1NitritesIBA
01/2021
1Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric
01/2021
1Sodium ChlorideFDA LinkGeneric
01/2021
1sodium nitrateIBA
01/2021
1AZD0156IBA
01/2021
13- amino- 6- (4- (methylsulfonyl)phenyl)- N- phenylpyrazine- 2- carboxamideIBA
01/2021
1Drinking WaterIBA
01/2021
1NitratesIBA
01/2021
1Histones (Histone)IBA
01/2021
1Dietary SodiumIBA
11/2020
1SaltsIBA
11/2020
1RoscovitineIBA
01/2020
1Cyclin-Dependent Kinase 2IBA
01/2020
1AlbuminsIBA
01/2020
1CollagenIBA
01/2019
1Arginine Vasopressin (Argipressin)IBA
01/2018
1Mechanistic Target of Rapamycin Complex 2IBA
01/2016
1LuciferasesIBA
12/2015
1Immunoglobulin G (IgG)IBA
01/2014
1TOR Serine-Threonine KinasesIBA
01/2014
1CytokinesIBA
05/2013
1Chemotactic FactorsIBA
05/2013
1Biological ProductsIBA
05/2013
1Inflammation MediatorsIBA
05/2013
1DiureticsIBA
01/2011
1Cyclin D1IBA
01/2011
1Retinoblastoma ProteinIBA
01/2011
1CyclinsIBA
01/2011

Therapy/Procedure

6Therapeutics
11/2015 - 01/2006
3Intraperitoneal Injections
01/2016 - 07/2005
1Pain Management
05/2015